French Scientists Discover Rare Blood Type in One Woman
A novel human blood type, dubbed “Gwada negative,” has been discovered in a 68-year-old woman from Guadeloupe, marking the first new blood group system identified in years and the 48th recognized globally. The discovery stemmed from routine pre-surgery tests in 2011 where her blood reacted to all known donor types, leading to a research endeavor. Through advanced genome sequencing, researchers identified a mutation in the PIGZ gene, which altered protein binding on red blood cells, creating antibodies that would reject all transfused blood except her own, making her only eligible for autologous transfusions. The French researchers who made the discovery are now searching Caribbean donor databases for other individuals with the rare genetic variation.
John Q. Hosedrinker