Pathogens

Ancient DNA Uncovers 37,000 Years of Human Infections and Evolutionary Impact

Scientists have constructed a 37,000-year timeline of human infections by analyzing ancient DNA from 1,313 individuals, revealing 214 pathogens. This research, led by Eske Willerslev, shows that the transition to farming around 6,500 years ago coincided with the emergence of zoonotic diseases. The study highlights how pathogens, like the plague bacterium, emerged and evolved, shaping human history and genetic variations through waves of infections linked to migrations and the domestication of animals. Furthermore, this ancient data provides valuable insights for modern medicine, aiding in the understanding of vaccine development and anticipating future mutations.

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