Gene Networks

South Korean Scientist Discovers Molecular Switch to Reverse Cancer Cells

Professor Kwang-Hyun Cho’s research team has developed a novel technology to reverse cancer by targeting a molecular switch active during the critical transition from normal to cancerous cells. By analyzing the genetic network at this precise moment of change, the team identified a mechanism that can revert cancer cells to a normal state without killing them. This systems biology approach utilizes single-cell RNA sequencing data to construct computer models of gene networks, allowing for the discovery of these crucial reversal switches. Experimental validation on colon cancer cells confirmed the ability of these identified switches to restore normal cell characteristics, paving the way for new reversion therapies.

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