New Injection Restores Knee Cartilage
A new injection that blocks an age-linked protein, 15-PGDH, has demonstrated the ability to regrow knee cartilage in older mice and prevent arthritis after knee damage. This approach works by allowing the repair signal prostaglandin E2 to remain active longer, prompting existing cartilage cells to rebuild the joint surface. Human knee tissue treated with the same blocker also showed signs of new cartilage formation in laboratory settings, suggesting a promising therapeutic avenue beyond current pain management and joint replacement options. Researchers are now planning carefully controlled clinical trials to determine if this injection can safely and effectively regenerate cartilage in humans.
John Q. Hosedrinker