Antibody Blocks Nearly All HIV Variants: Potential for Treatment
Researchers have identified a highly effective antibody, 04_A06, that neutralizes a wide range of HIV-1 variants, including those resistant to other antibodies. This antibody, discovered by an international team, demonstrated broad activity in laboratory tests, neutralizing 98.5% of tested HIV strains and permanently reducing viral load in humanized mice. The unique structure of 04_A06, including an exceptionally long amino acid chain, allows it to target difficult-to-access, highly conserved areas of the virus, overcoming classic resistance mechanisms. With promising results in computer models predicting high protective efficacy, this antibody is being further developed for clinical trials through a license to Vir Biotechnology, Inc.
John Q. Hosedrinker